In2262，EarthforceCaptainElizabethLochleyisappointedtocommandBabylon5.ThestationgrowsinitsroleasasanctuaryforroguetelepathsrunningfromthePsiCorps，resultinginconflict.G'Kar，formerNarnambassadortoBabylon5，becomesunwillinglyaspiritualiconafterabookispublishedthathewrotewhileincarceratedduringtheNarn-CentauriWar.TheDrakh，formeralliesoftheShadowswhoremainedinthegalaxy，takecontrolofRegentVirinionCentauriPrimethroughaparasiticcreaturecalledaKeeper，theninciteawarbetweentheCentauriandtheInterstellarAlliance，inordertoisolatetheCentaurifromtheAllianceandgainamalleablehomeworldforthemselves.CentauriPrimeisdevastatedbyNarnandDraziwarshipsandLondoMollaribecomesemperor，acceptingaDrakhKeeperunderthreatofthecompletenucleardestructionoftheplanet（Portionsoftheendofhisreignareseeninvariousprescientvisionsthroughouttheseries。TheyshowMollariandformernemesis（andlaterfriend）G'Karsixteenyearsinthefuturedyingateachother'sthroats，seeminglyoutoftheirgrudge.Itisgraduallyrevealedthattherewasamuchmore ˚F潛伏的潛台詞，使Mollari變得奴隸般的束縛和疲倦的生活，hisDrakhKeeperawakensandstranglesG'Karinreturn.VirCotto，Mollari'sloyalandmoremoralaide，succeedshimasemperor，freeofDrakhinfluence.SheridanandDelennmarryandmovetoMinbar，alongwiththeheadquartersoftheInterstellarAlliance.G'KarleavesBabylon5toescapehisunwantedfameandexploretherim.GaribaldialsomarriesandsettlesdownonMars.MostoftheothermaincharactersleaveB5.Nineteenyearslateronthevergeofdeath，SheridantakesafinaltriptotheobsoleteBabylon5stationbeforeitsdecommissioning.SheridanapparentlydiesbutisclaimedbytheFirstOnes巴比倫5號車站在謝里登（Sheridan）離開後不久就被摧毀，其存在不再長期存在於聯盟之上，它的存在已不再是外交目的。